GH Wellness A.P. Sinta – The King of Bitters


A.P. Sinta (Andrographis paniculata Sinta) is a good and effective anti-diarrheal, anti-pyretic, anti-infective, anti-inflammatory, anti-bacterial, anti-typhoid, anti-fungal, anti-malarial, anti-dengue, anti-hepatotoxic, anti-cancer, tonic and immune boosting. It is found effective in preventing blood clots and re-clogging of arteries post-angioplasty. The Sinta herb is found to activate fibrinolysis (dissolution of blood clots) and has a blood pressure lowering effect. It may inhibit the growth of human breast cancer cells and it has an anti-viral activity in HIV and AIDS, found to increase AZT’s (azidothymidine) stability to inhibit HIV replication. It has a preventive effect for diabetic nephropathy and it can be used for therapy, in patients with snakebite envenomation. It is a promising treatment for the subjective symptoms of acute upper respiratory tract infection.

What is Andrographis paniculata?

Andrographis paniculata is an annual herbaceous plant in the family Acanthaceae, native to India and Sri Lanka.

It is widely cultivated in Southern and Southeastern Asia, where it has been traditionally used to treat infections and some diseases. Mostly the leaves and roots were used for medicinal purposes.

Andrographis paniculata is an erect annual herb extremely bitter in taste in all parts of the plant body. The plant is known in north-eastern India as Maha-tita, literally “king of bitters”, and known by various vernacular names. As an Ayurveda herb it is known as Kalmegh or Kalamegha, meaning “dark cloud”. It is also known as Bhui-neem, meaning “neem of the ground”, since the plant, though being a small annual herb, has a similar strong bitter taste as that of the large Neem tree (Azadirachta indica). In Malaysia, it is known as Hempedu Bumi, which literally means ‘bile of earth’ since it is one of the most bitter plants that are used in traditional medicine.

Medicinal use:

Since ancient times, A. paniculata is used in traditional Siddha and Ayurvedic systems of medicine as well as in tribal medicine in India and some other countries for multiple clinical applications.

The herb has a number of purported medicinal uses, although research has found evidence of its effectiveness is limited to treatment of upper respiratory infection, ulcerative colitis and rheumatic symptoms; in particular, there is no evidence of its effectiveness in cancer treatment.

According to the Mayo Clinic Book of Alternative Medicine, “A specific product (andrographis combined with Eleutherococcus senticosus) may shorten the duration and lessen the symptoms of common cold.” It also says, “Pregnant women shouldn’t use andrographis because it could terminate pregnancy.”

In one Chilean study from 1999, the herb had a significant drying effect on the nasal secretions of cold sufferers who took 1,200 milligrams of andrographis extract daily for five days. A 2012 study suggested that Andrographis paniculata extracts may have the potential to be used as a mosquito repellant. A 2006 study reported that extracts of Andrographis exhibited potent anti-inflammatory effects and antioxidant actions in mice.